What classification does Brompheniramine fall under?

Brompheniramine is classified as a 1st-generation antihistamine. This classification is characterized by its ability to cross the blood-brain barrier, leading to central nervous system (CNS) effects, including sedation. 1st-generation antihistamines, such as Brompheniramine, are effective in alleviating allergic symptoms by blocking the H1 histamine receptors, but they are also known for their sedative properties and potential side effects, such as drowsiness and dry mouth.

In contrast, 2nd-generation antihistamines are designed to minimize CNS penetration, making them less sedating and more suitable for daily use without the drowsiness associated with 1st-generation drugs. Non-sedating antihistamines typically refer to those 2nd-generation options. Intranasal antihistamines, on the other hand, are formulated specifically for nasal administration and focus more on localized effects rather than systemic ones. Therefore, the classification of Brompheniramine as a 1st-generation antihistamine accurately describes its properties and effects in comparison to other types of antihistamines.