NBEO Pharmacology Practice Exam

Fluticasone, particularly when administered intranasally for conditions like allergic rhinitis, has been associated with an increased risk of cataracts. Steroids, including inhaled and intranasal forms, can lead to lens opacification over time, which manifests as cataracts. Long-term use of corticosteroids is a well-documented risk factor for cataract development due to their effects on protein metabolism within the lens and their ability to influence ocular pressure.

While other side effects may arise from the use of intranasal steroids, such as localized irritation or nasal dryness, cataracts remain a significant ocular concern, particularly in patients using these medications frequently or over extended periods. Understanding the risk of cataracts reinforces the need for patient education regarding the long-term use of fluticasone and the importance of regular eye examinations for those who are at higher risk for ocular complications.