NBEO Pharmacology Practice Exam

The antibiotic that is considered fortified with a penicillinase inhibitor is Augmentin. Augmentin is a combination antibiotic that includes amoxicillin and clavulanate potassium. Clavulanate potassium is a penicillinase inhibitor that helps to protect amoxicillin from being broken down by beta-lactamase enzymes, which are produced by some bacteria to resist penicillin antibiotics. This combination enhances the efficacy of amoxicillin against resistant bacterial strains.

In contrast, amoxicillin on its own does not contain a penicillinase inhibitor, making it less effective against beta-lactamase producing organisms. Dicloxacillin is a penicillinase-resistant penicillin but does not include an inhibitor, and cephalexin is a cephalosporin that does not contain any penicillinase inhibitors either. Therefore, Augmentin is the choice that best represents an antibiotic fortified with a penicillinase inhibitor.