Cephalexin is classified as which generation of antibiotics, while ceftriaxone is classified as which generation?

Cephalexin is classified as a first-generation cephalosporin antibiotic. It is primarily effective against Gram-positive bacteria and is commonly used to treat infections caused by organisms like Streptococcus and Staphylococcus. Its spectrum of activity includes some Gram-negative bacteria but is more limited compared to later generations.

Ceftriaxone, on the other hand, is a third-generation cephalosporin. This class of antibiotics is characterized by its broader spectrum of activity, particularly against Gram-negative bacteria, including those that are resistant to first- and second-generation cephalosporins. Ceftriaxone is often used for more severe infections and has the ability to penetrate the central nervous system, making it effective for treating conditions like meningitis.

Understanding the classification of cephalosporins helps to determine their appropriate use in clinical settings, as each generation boasts a distinct profile of antimicrobial activity and clinical indications, which is crucial for effective treatment strategies.