In which condition should prostaglandin analogs not be used?

Prostaglandin analogs are primarily utilized in the management of glaucoma because they effectively lower intraocular pressure by increasing the outflow of aqueous humor. However, their use is not appropriate in the context of uveitis. Uveitis is an inflammatory condition of the uveal tract, which can lead to complications such as an increase in intraocular pressure and potentially exacerbate the inflammatory response.

In patients dealing with uveitis, the inflammatory process needs careful management. Prostaglandin analogs may exacerbate inflammation and worsen the symptoms due to their effects on the eye's tissues. The primary treatment approaches for uveitis often include corticosteroids and immunosuppressive agents, which specifically target inflammation rather than adding to it.

In contrast, prostaglandin analogs are suitable for conditions like glaucoma, where the primary concern is lowering intraocular pressure, and they can be beneficial in managing dry eye syndrome by increasing tear production through enhanced aqueous humor outflow. In conjunctivitis, these agents are generally not directly used but do not interfere with the fundamental management of the condition.

Thus, due to the potential exacerbation of inflammatory responses and complications associated with uveitis, prostaglandin analogs are not indicated in this condition.