Patients with which condition should avoid using topical beta-blockers?

Topical beta-blockers are generally contraindicated in patients with hyperthyroidism due to the potential for exacerbating the condition. In hyperthyroid patients, there is an increased sensitivity to beta-adrenergic stimulation, and the use of beta-blockers can mask certain signs of hyperthyroidism, such as tachycardia, potentially leading to a delay in diagnosis and treatment. While topical beta-blockers can be effective in managing conditions like glaucoma, their systemic absorption can have significant effects in individuals with hyperthyroidism, making it crucial for these patients to avoid their use.

In contrast, beta-blockers are commonly utilized in treating hypertension and glaucoma, as they can effectively lower intraocular pressure and help manage high blood pressure. Rheumatoid arthritis is not directly affected by the use of topical beta-blockers, although caution is always advisable with any medication in patients with chronic conditions. Thus, in the context of topical beta-blockers, hyperthyroidism presents a particular risk that justifies avoidance, emphasizing the need for careful consideration of systemic effects in certain populations.