Pyridostigmine is primarily used for which condition?

Pyridostigmine is primarily used for Myasthenia Gravis, which is an autoimmune disorder characterized by weakness and rapid fatigue of the voluntary muscles. The mechanism of action for pyridostigmine involves inhibiting the enzyme acetylcholinesterase, which leads to increased levels of acetylcholine at the neuromuscular junction. This enhancement of acetylcholine activity helps to improve muscle function in individuals suffering from Myasthenia Gravis by compensating for the decreased receptor activity that occurs due to the disease.

In contrast, while other conditions mentioned can involve muscular symptoms or nerve interactions, they do not primarily utilize pyridostigmine as a treatment. For instance, accommodative esotropia involves issues with eye alignment and involves different therapeutic approaches; glaucoma is typically treated with different classes of medications aimed at lowering intraocular pressure; and Parkinson's disease is treated with dopaminergic agents rather than acetylcholinesterase inhibitors. Thus, the correct answer clearly indicates that pyridostigmine's primary application is in the management of Myasthenia Gravis.