Topical beta-blockers should be used cautiously in which of the following patient groups?

Topical beta-blockers can potentially affect the respiratory system, particularly in patients with asthma. In such individuals, beta-blockers may provoke bronchoconstriction due to their mechanism of action, which is focused on blocking beta-adrenergic receptors. This is especially important for non-selective beta-blockers, which can block both beta-1 and beta-2 receptors, leading to respiratory complications in asthmatic patients.

Although it is true that diabetes patients should monitor their glucose levels as beta-blockers may mask hypoglycemic symptoms, the primary concern with the use of topical beta-blockers is related to their effect on the respiratory system, making the asthmatic population particularly vulnerable. Therefore, caution is advised with the use of beta-blockers in patients with asthma to avoid severe respiratory events.