What is a known contraindication for tetracycline antibiotics?

Tetracycline antibiotics are contraindicated during pregnancy due to their potential to cause harm to the developing fetus. Specifically, these medications can affect bone growth and result in permanent discoloration of teeth. The chelation of calcium by tetracyclines can interfere with the development of fetal skeletal structures, leading to adverse effects on bone density and development. Because of these significant risks, tetracycline use is strictly avoided in pregnant individuals to ensure the health and safety of both the mother and the fetus.

Using tetracycline in pregnant patients poses a serious consideration that outweighs the benefits of treating infections that are susceptible to these antibiotics. Therefore, health care providers typically recommend alternative antibiotics that are safer for use during pregnancy.