Which beta-blocker combination includes Timolol and 2% Dorzolamide?

The combination of Timolol and 2% Dorzolamide is known as Cosopt. This formulation is used in the treatment of elevated intraocular pressure in conditions such as glaucoma or ocular hypertension. Timolol, a non-selective beta-blocker, reduces aqueous humor production, contributing to lower intraocular pressure. Dorzolamide, a carbonic anhydrase inhibitor, works by decreasing bicarbonate secretion and consequently reduces the production of aqueous humor as well. The synergistic effect of these two medications makes Cosopt an effective option for managing intraocular pressure.

Other formulations mentioned in the options do not contain both Timolol and Dorzolamide; for instance, Combigan contains Timolol and Brimonidine, while Travatan includes Travoprost. Azarga is a combination of Brinzolamide and Timolol as well. This distinction among the combinations is crucial for understanding their therapeutic uses in ocular conditions.