Which condition can Ketoconazole be used to treat?

Ketoconazole is an antifungal agent belonging to the azole class. It is primarily used to treat fungal infections by inhibiting ergosterol synthesis, which is essential for fungal cell membrane integrity. While it is effective against a variety of fungal infections, including dermatophyte infections and systemic mycoses, its use in ocular conditions, particularly for severe fungal corneal ulcers, is of note.

Severe fungal corneal ulcers are serious eye conditions that necessitate appropriate antifungal treatment to prevent vision loss. Ketoconazole can be employed in these cases since it has demonstrated efficacy against certain filamentous fungi that can lead to corneal infections. This makes it a suitable choice for treating such ocular fungal infections.

It’s important to recognize that while Ketoconazole is effective for this particular condition, it may not be the preferred choice for all types of fungal infections due to potential side effects and the availability of other antifungal agents that might be more effective or better tolerated in specific situations.