Which condition is associated with all tetracyclines, excluding Doxycycline?

Tetracyclines are a class of antibiotics that can pose significant risks when administered to certain populations. In particular, renal failure is a condition that affects the excretion of many tetracyclines, leading to increased serum concentrations and the potential for toxicity. However, Doxycycline is unique within this class because it is primarily excreted through the liver, making it a safer option for patients with renal impairment. Therefore, it is the other tetracyclines that are particularly contraindicated in patients with renal failure due to their dependence on renal excretion.

This specificity of doxycycline allows it to be used more safely in certain populations, such as patients with chronic kidney disease, where the risk of elevated drug levels and associated side effects is paramount with the other tetracycline antibiotics.