Which medication is classified as a topical NSAID?

Diclofenac sodium is classified as a topical NSAID (nonsteroidal anti-inflammatory drug) due to its ability to reduce inflammation and relieve pain when applied locally to the skin or mucous membranes. It works by inhibiting the cyclooxygenase (COX) enzymes, which play a key role in the synthesis of prostaglandins—compounds that mediate inflammation and pain. This makes diclofenac sodium particularly effective in treating localized conditions, such as musculoskeletal pain or inflammation around the eyes.

In contrast, fluorometholone, dexamethasone, and prednisolone acetate are corticosteroids. These medications primarily have anti-inflammatory effects through different mechanisms, such as suppression of leukocyte migration and immune response modulation, rather than acting directly on COX enzymes like NSAIDs. While corticosteroids can also be applied topically to manage inflammation, they do not fall under the category of NSAIDs and are used differently in clinical practice.