Which of the following describes the action of Propranolol and Labetalol?

Propranolol and Labetalol are classified as non-selective beta-1 and beta-2 antagonists, which means they block the activity of both beta-1 and beta-2 adrenergic receptors in the body. This action leads to a decrease in heart rate and myocardial contractility (due to beta-1 blockade), as well as vasodilation and bronchodilation effects (due to beta-2 blockade).

Propranolol is commonly used for conditions like hypertension, anxiety, and migraine prophylaxis, while Labetalol is particularly useful in managing hypertension, especially in acute settings like hypertensive emergencies or in pregnant patients. By inhibiting these receptors, both drugs help to manage the body's response to stress hormones like epinephrine and norepinephrine, ultimately leading to lowered blood pressure and reduced heart workload.

The other options do not accurately describe the action of these drugs, as they either refer to specific classes of medications that do not fit this description or indicate mechanisms not related to beta receptor antagonism.