Which of the following medications has anticholinergic effects?

Cyclobenzaprine is a medication that is classified as a muscle relaxant and is known to have anticholinergic properties. The anticholinergic effects arise due to the drug's ability to block acetylcholine at muscarinic receptors, which can lead to symptoms such as dry mouth, constipation, urinary retention, and blurred vision. These side effects are particularly significant in certain populations, such as the elderly, who may be more sensitive to anticholinergic medications.

In contrast, acetaminophen is primarily an analgesic and antipyretic agent without anticholinergic activity. Tramadol, while it has a complex mechanism of action involving opioid receptors, does not exhibit notable anticholinergic properties. Oxycodone, also an opioid analgesic, primarily exerts its effects through mu-opioid receptor agonism and does not have significant anticholinergic activity. Thus, cyclobenzaprine stands out in this group for its anticholinergic effects.